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Team

Prof. Yuval Ebenstein

Principal investigator

Yuval Ebenstein studied chemistry and physics at the Hebrew University in Jerusalem, Israel, where he also completed his Ph.D. in physical chemistry with Prof. Uri Banin, studying the photophysical properties of individual semiconductor nanocrystal quantum dots (QDs).

He then moved to work as a postdoc with Prof. Shimon Weiss at UCLA where he used QDs to light-up individual DNA binding proteins and map them along bacteriophage genomes. 

In the summer of 2011 he set-up the NanoBioPhotonix Lab in the department of chemical physics, school of chemistry at Tel Aviv University. 

uv@tauex.tau.ac.il   |   +972-54-3188316   |  +972-3-6408901

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Dr. Jasline Deek

Lab manager

Jasline ensures that the lab operates smoothly by conducting and managing various research activities and projects in the lab.

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Dr. Miri Neaman

Post-Doc

Miri is a post doc and hematologist in Tel Aviv medical center. Her research field is studying methylation and hydroxy-methylation patterns in Hematological malignancies using microarrays.

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Jonathan Jeffet

Ph.D. Student

Jonathan is developing a high-throughput single-molecule detection technique.

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Assaf Grunwald 

Post-Doc student

Assaf develops a new labeling and analysis method for mapping DNA

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Sigal Avraham

Ph.D. student

Sigal is working on Fluorescent detection and global quantification of epigenetic modifications in various cancer types. In my research I developed a high throughput assay for simultaneous enzymatic labeling of 5mC and 5hmC content using multi-sample array slide allowing sensitive analysis that can potentially be used for medical diagnostics.

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Uri Bertocchi

Ph.D. student

Uri is investigating the application of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) as novel potential biomarkers for a range of psychiatric disorders. This research aims to enhance our understanding and therapeutic capabilities for these illnesses, potentially leading to more effective and targeted treatments.

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Lanna Beri

MSc student

Improve resolution and overcome the diffraction limit of light with confocal spinning disk microscope (CSD) and Spectral Image Scanning Microscopy (ISM).  Encode color into spatial read-out in the image plane with continuously controlling Spectral-resolution (CoCoS) and combine it with the improved resolution.

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Eliran Eitan

MSc student

Eliran develops a Nanopore long read sequencing model that will identify exclusively synthetic modification marker, that will allow easy detection of any epigenetic modification.

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Tahir Detinis Zur

Ph.D. Student

Tahir is  working on advanced cytogenetics for the structural characterization of the human genome

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Sapir Margalit

Ph.D. Student

Sapir develops a sensitive method for 5-hydroxymethylcytosine quantification in genomic DNA.

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Dr. Sayan Mondal (Alumni)

Post-Doc

Sayan is Developing a liquid biopsy for lung cancer by optical quantification of microRNA.

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Sivan Fishman (Alumni)

Ph.D. student 

Sivan is a joint student with Prof. Michael Gozin from the organic chemistry department. She works on chemical modification of DNA.

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Gil Nifker (Alumni)

Ph.D. Student

Gil is a joint student with Prof. Micha Fridman from the organic chemistry department and works on synthesizing and applying epigenetic modification cofactors for DNA labeling.

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Gal Goldner (Alumni)

MSc student

Gal is working on Using Nanopore sequencing in order to develop a new epigenetic analysis tool for breast cancer genescription here

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Dmitry Torchinsky (Alumni)

Research associate

Dima is developing imaging based single molecule analysis techniques and instrumentation

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Dr. Zuzana Tulpová (Alumni)

Post-Doc

Zuska is involved in projects combining single molecule genome mapping and next generation sequencing focused on epigenetics.

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Dr. Yael Michaeli (Alumni)

Lab manager

Yael is responsible for project management and support of all things "bio".She is also developing new epigenetic analysis tools for single-molecule genome mapping and next generation sequencing.

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Adaya Ben Moshe (Alumni)

MSc student

Adaya is working on the Usage of labeling cfDNA for various applications

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Noa Gilat (Alumni)

Ph.D. Student

Noa is developing Optical detection methods of chemical DNA modifications in the context of DNA related diseases

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Hila Sharim (Alumni)

Ph.D. student

Hila works on various aspects of DNA damage distribution by next generation sequencing and single-molecule techniques.

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Dr. Shahar Zirkin (Alumni)

Research associate 

Shahar graduated from Bar Ilan University and is now working on DNA damage and epigenetic alterations in cancer.

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Dr. Christian Heck (Alumni)

Post-Doc

Christian is a postdoc who came from Potsdam University in Germany.

He works on the combination of DNA origami and epigenetic research.

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Tslil Gabrieli (Alumni)

Ph.D. student

Tslil works on single-molecule epigenetic mapping.

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Dr. Tamar Shahal (Alumni)

Research associate

Tamar is involved in several projects in the lab but focuses mainly on the development and application of high-throughput analysis of 5-hydroxymethylcytosine (5hmC) in genomic DNA.

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Dr. Rani Arielly (Alumni)

Postdoctoral fellow

Rani studied physics and then garduated with Prof. Yoram Selzer, where he studied mulecular junctions.

Rani splits his time between developing new code for data nanalysis and developing new DNA imaging devices.

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Amit Shwartz (Alumni)

Ph.D. Student

Recent studies have found an association between reduced 5hmc levels and various cancer types. We set forward to test this association by quantifying
5-Hydroxymethylcytosine (5hmc) in different blood cancer samples and comparing them to healthy controls.

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Dr. Michal Levi-Sakin (Alumni)

Postdoctoral fellow

Michal worked on chemo-enzymatic modifications of DNA for epigenetic studies.

She is now a post doctoral fellow with Prof. Pui Kwok at UCSF

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Yael Gluckman (Alumni)

M.Sc. student

Yael worked on copy number variation detection and now pursuing a career in the biomed industry

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Dr. Yifat Berkov-Zrihen (Alumni)

Postdoctoral fellow

Yifat graduated from the lab of Prof. Micha Fridman specializing in the organic synthesis. She developed synthetic factors for bioconjugation of epigenetic marks.

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Asaf Kobo (Alumni)

M.Sc. student

Assaf studied physical aspects of DNA mapping in nanochannels. He now works Elbit Systems.

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Mika Bell 

M.Sc. student

Mika is developing a pipeline for pattern analysis of a new and advanced DNA microarray methylation array for different types of cancer, using computational tools and statistical models to analyze large datasets of DNA methylation patterns, identifying differentially methylated regions associated with cancer, and optimizing the pipeline for scalability and reproducibility. The ultimate goal is to gain new insights into the molecular mechanisms of cancer development and progression.

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